Cellulose Nanofiber Platform for Electrochemical Sensor Device: Impedance Measurement Characterization and Its Application for Ethanol Gas Sensor
Abstract
Bioplastics such as cellulose nanofibers (CNF) are widely used in daily life as an alternative to plastics. CNF is also considered a biodegradable, readily disposable, and low-cost material, making it suitable as a sensor platform. The mechanically treated CNF has both hydrophobic and hydrophilic properties where the hydrophobic sides bond strongly with MWCNTs to provide conductivity on the CNF sheet, while the hydrophilic sides allow the target component to be adsorbed on its laminated structure and react with the electrode surface. From an electrochemical measurement of ferricyanide solution indicated that the MWCNTs modified CNF could act well as electrode. Furthermore, the thin-sheet electrode successfully detected ethanol based on a direct electron transfer (DET) between PQQ-ADH and the MWCNTs on the electrode surface. Aside from its lightweight properties, the developed CNF electrode possesses excellent stretchability, flexibility, and adjustability to human skin, making it ideal for a future wearable skin gas sensor.
References
Wilcox C, Van Sebille E, Hardesty BD. Threat of plastic pollution to seabirds is global, pervasive, and increasing. Proceedings of the National Academy of Sciences. 2015; 112(38): 11899-11904.
Kumar R, Manna C, Padha S, Verma A, Sharma P, Dhar A, Ghosh A, Bhattacharya P. Micro(nano)plastics pollution and human health: How plastics can induce carcinogenesis to humans? Chemosphere. 2022; (298): 134267.
Reddy RL, Reddy VS, Gupta G A. Study of bio-plastics as green and sustainable alternative to plastics. International Journal of Emerging Technology and Advanced Engineering. 2013; 3(5): 76-81.
Ghaderi M, Mousavi M, Yousefi H, Labbafi M. All-cellulose nanocomposite film made from bagasse cellulose nanofibers for food packaging application. Carbohydrate polymers. 2014; 104: 59-65.
Pandey A. Pharmaceutical and biomedical applications of cellulose nanofibers: a review. Environmental Chemistry Letters. 2021; 19(3): 2043-2055.
Sakwises L, Rodthongkum N, Ummartyotin S. SnO2- and bacterial-cellulose nanofiber-based composites as a novel platform for nickel-ion detection. Journal of Molecular Liquids. 2017; 248: 246-252.
Nogi M, Kim C, Sugahara T, Inui T, Takahashi T, Suganuma K. High thermal stability of optical transparency in cellulose nanofiber paper. Applied Physics Letters. 2013; 102(18): 181911.
Yano H, Sugiyama J, Nakagaito AN, Nogi M, Matsuura T, Hikita M, Handa K. Optically transparent composites reinforced with networks of bacterial nanofibers. Advanced Materials. 2005; 17(2): 153-155.
Moro G, Bottari F, Van Loon J, Du Bois E, De Wael K, Moretto LM. Disposable electrodes from waste materials and renewable sources for (bio) electroanalytical applications. Biosensors and Bioelectronics. 2019; 146: 111758.
Liang X, Long G, Fu C, Pang M, Xi Y, Li J, Han W, Wei G, Ji Y. High performance all-solid-state flexible supercapacitor for wearable storage device application. Chemical Engineering Journal. 2018; 345: 186-195.
Gao K, Shao Z, Wang X, Zhang Y, Wang W, Wang F. Cellulose nanofibers/multi-walled carbon nanotube nanohybrid aerogel for all-solid-state flexible supercapacitors. RSC advances. 2013; 3(35): 15058-15064.
Yuan S, Zheng Y, Chua C K, Yan Q, Zhou K. Electrical and thermal conductivities of MWCNT/polymer composites fabricated by selective laser sintering. Composites Part A: Applied Science and Manufacturing. 2018; 105: 203–213.
Arakawa T, Suzuki T, Tsujii M, Iitani K, Chien P, Ye M, Toma K, Iwasaki Y, Mitsubayashi K. Real-time monitoring of skin ethanol gas by a high-sensitivity gas phase biosensor (bio-sniffer) for the non-invasive evaluation of volatile blood compounds. Biosensors and Bioelectronics. 2019; 129: 245-253.
Arakawa T, Aota T, Iitani K, Toma K, Iwasaki Y, Mitsubayashi K. Skin ethanol gas measurement system with a biochemical gas sensor and gas concentrator toward monitoring of blood volatile compounds. Talanta. 2020; 219: 121187.
Ye M, Chien PJ, Toma K, Arakawa T, Mitsubayashi K. An acetone bio-sniffer (gas phase biosensor) enabling assessment of lipid metabolism from exhaled breath. Biosensors and Bioelectronics. 2015; 73: 208–213.
Chien PJ, Suzuki T, Tsujii M, Ye M, Minami I, Toda K, Otsuka H, Toma K, Arakawa T, Araki K, Iwasaki Y, Shinada K, Ogawa Y, Mitsubayashi K. Biochemical Gas Sensors (Biosniffers) Using Forward and Reverse Reactions of Secondary Alcohol Dehydrogenase for Breath Isopropanol and Acetone as Potential Volatile Biomarkers of Diabetes Mellitus. Analytical Chemistry. 2017; 89(22): 12261–12268.
Shin W, Itoh T, Izu N. Health care application of gas sensors—Medical devices of breath analysis—. Synthesiology English edition. 2015; 8(4): 211-219.
Anderson JC, Babb AL, Hlastala MP. Modeling soluble gas exchange in the airways and alveoli. Annals of biomedical engineering. 2003; 31(11): 1402-1422.
Mochalski P, King J, Unterkofler K, Hinterhuber H, Amann A. Emission rates of selected volatile organic compounds from skin of healthy volunteers. Journal of chromatography B. 2014; 959: 62-70.
Jones AW, Andersson L. Comparison of ethanol concentrations in venous blood and end-expired breath during a controlled drinking study. Forensic science international. 2003; 132(1): 18-25.
Stetter J R, Li J. Amperometric gas sensors a review. Chemical reviews. 2008; 108(2): 352-366.
Tominaga M, Kuwahara K, Tsushida M, Shida K. Cellulose nanofiber-based electrode as a component of an enzyme-catalyzed biofuel cell. RSC Advances. 2020; 10(37): 22120-22125.
Kondo T, Kose R, Naito H, Kasai W. Aqueous counter collision using paired water jets as a novel means of preparing bio-nanofibers. Carbohydrate Polymers. 2014; 112: 284–290.
Yokota S, Kamada K, Sugiyama A, Kondo T. Pickering emulsion stabilization by using amphiphilic cellulose nanofibrils prepared by aqueous counter collision. Carbohydrate Polymers. 2019; 226: 115293.
Sandford C, Edwards M A, Klunder K, Hickey D P, Li M, Barman, K, Sigman M S, White H S, Minteer S D. A Synthetic Chemist’s Guide to Electroanalytical Tools for Studying Reaction Mechanisms. Chemical Science. 2019; 10: 6404-6422.
Franco J H, Minteer S D, de Andrade A R. Product Analysis of Operating an Ethanol/O2Biofuel Cell Shows the Synergy between Enzymes within an Enzymatic Cascade. Journal of The Electrochemical Society. 2018; 165(9): H575–H579.
Copyright (c) 2022 Citra Dewi Rakhmania, Shaimah Rinda Sari, Yosyi Izuddin Azhar, Airi Sugita, Masato Tominaga (Author)
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